NAD loss primarily shows up in stressed tissues like liver, muscle, or cochlea even without noticeable changes in blood Healthy people often maintain typical blood NAD, but obesity, alcoholism, mitochondrial disease, and chronic inflammation can severely disrupt NAD inside organs As a basic cofactor cells need for energy production and everyday repair, NAD loss means organs become less resilient to stress So rather than NAD simply "declining with age," it's age-linked diseases and lifestyle stre
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