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These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...
After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...
The accumulation and prion‐like propagation of α‐synuclein and other amyloidogenic proteins are associated with devastating neurodegenerative diseases. Metazoan heat shock protein HSP70 and its ...
Gasdermin‐D (GSDMD), a member of the gasdermin protein family, mediates pyroptosis in human and murine cells. Cleaved by inflammatory caspases, GSDMD inserts its N‐terminal domain (GSDMD Nterm) into ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. I spent the winters of my youth traveling ...
image image N‐linked glycosylation of the perforin C‐terminus inhibits oligomerisation of perforin monomers, protecting the host cell from premature pore formation. Removal of this glycan in secretory ...
The genetic code was deciphered more than 50 years ago, but we are only now becoming aware of a second, hidden code. It is the concept of “codon optimality” that enters the scene of developmental and ...
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Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system ...
In order to understand how PX‐BAR proteins perform their functions in the progression of membrane deformation, it is of importance to reveal the details of this structural unit. We show here that ...