These results provide the first in vivo validation that Tnpo3 overexpression restores alternative splicing and cardiac ...

Dr. Peder Myhre: Welcome listeners to this week's issue of Circulation on the Run in the week of September 2nd. And my name ...

Background: In addition to the risk of stroke, patients undergoing transcatheter aortic valve implantation (TAVI) are susceptible to a decline in neurocognitive function. This may occur due to ...

Background: The clinical utility of risk scores to guide treatment decisions and improve clinical outcomes has rarely been prospectively evaluated. This study aimed to evaluate whether a ...

Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce the risk of cardiovascular death or worsening heart failure (HF) in outpatients with HF. Data are limited regarding initiation in ...

Background: Anthracycline- and trastuzumab-associated cardiotoxicity may lead to cardiac dysfunction and dose reduction or halt in potentially life-saving adjuvant cancer therapy. Whether angiotensin ...

When a manuscript is ready for submission, please proceed to the manuscript submission site. Those manuscripts that are revised or ultimately accepted will be required to be formatted by the authors ...

This real‐world evidence study of 6961 patients was conducted by applying pattern recognition methods to parse and extract CAC scores from CCTAs conducted as part of clinical screening for CVD risk.

The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk ...

BACKGROUND: Whereas antiphospholipid syndrome (APS) is best known for increasing the risk of macrovascular thrombosis, APS vasculopathy is characterized by the abnormal proliferation of endothelial ...

Background: Transcatheter aortic valve replacement (TAVR) is increasingly performed in younger, low surgical risk patients. This NOTION-2 study reports mid-term outcomes in low-risk patients aged ...

Background: Artificial intelligence (AI)-enhanced electrocardiogram (ECG) models are often designed to detect specific anatomical and functional cardiac abnormalities. Understanding the selectivity of ...