BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Protein aggregates, damaged organelles, and invading bacteria are identified and removed in healthy cells. An international ...

Researchers have developed a way to 3D print custom micrometer-sized structures directly into the interior of living cells.

Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and ...

Across biology labs, the idea that aging might be governed by a few crucial switches is moving from science fiction to bench science. Instead of treating growing old as a slow, inevitable decline, ...

After a century of false starts, scientists believe they have found a way to make cells burn more energy without the ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, ...

The mitochondrion, often referred to as the powerhouse of the cell, plays critical roles in cellular function, making it a prime organelle to target for fundamental studies, metabolic engineering, and ...

GBA1 mutations alone do not explain lysosomal dysfunction in PD. Loss of endosomal recycling proteins cripple this lysosomal enzyme. Without a protein called COMMD3, cells spit out would-be lysosomal ...