Children with hematologic malignancies continue to exhibit increased IPD risk despite an overall decline in pediatric IPD after the introduction of the PCV13 vaccine.

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

ConspectusNucleic acids are naturally decorated with various chemical modifications at nucleobases. Most nucleic acid modifications (NAMs) do not alter Watson–Crick base pairing but can regulate gene ...