Inflammation has to fight pathogens fast—but it can't get out of control. Researchers at the German Cancer Research Center ...

Plants rely on complex chemical defenses to survive attacks from pathogens, yet the genetic basis underlying the production ...

The researchers used a genetic tool called CRISPRi that can mute DNA sections without permanently cutting them. The tool was ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

A baby born with a rare and life-threatening genetic disorder has taken his first steps after receiving a groundbreaking, personalized gene editing treatment at Children’s Hospital of Philadelphia. KJ ...

The FDA has issued its stamp of approval to a new, cell-based option to treat Wiskott-Aldrich syndrome (WAS), marking the first therapy of its kind for the rare disease and making Italy’s Fondazione ...

Scientists have identified a protein that may be key to proper sperm formation. Without it, male mice produced no viable sperm, they found. A team at the RIKEN Center for Biosystems Dynamics Research ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

Instead of requiring personalized gene edits for each patient, the new approach could create a standardized method to use for many diseases. By Pam Belluck and Carl Zimmer Gene-editing therapies offer ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

Introduction: Phenylalanine ammonia-lyase (PAL), as the rate-limiting enzyme in plant phenylpropanoid metabolism, catalyzes the conversion of L-phenylalanine to trans-cinnamic acid and plays a pivotal ...