Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material ...

This valuable study identifies a novel regulator of stress-induced gene quiescence in C. elegans: the multi-Zinc-finger protein ZNF-236. The work provides evidence for an active mechanism that ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a double helix. That picture is still right, but it is no longer enough.

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted changes in gene function. Report: Claire Robinson and Prof Michael Antoniou ...

A gene therapy that targets a form of retinitis pigmentosa showed a signal to improve retinal function for up to 3 years after treatment, according to a small clinical trial. The phase 2 SKYLINE trial ...

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to ...

1 Department of Gastrointestinal Surgery, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. 2 School of Clinical Medicine, Youjiang Medical University for ...

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...

On July 30, World Athletics announced specifics on a new gene testing policy for athletes competing in the female category. To be eligible for the upcoming Tokyo World Athletics Championships, these ...

This study is valuable as it provides information about the genes regulated by sex hormone treatment in song nuclei and other brain regions and suggests candidate genes that might induce sexual ...