Children with hematologic malignancies continue to exhibit increased IPD risk despite an overall decline in pediatric IPD after the introduction of the PCV13 vaccine.

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Explore how AI-driven Smart Diagnostics are revolutionizing healthcare, as the market shifts from research to clinical practice. Discover the potential for premium diagnostics, pricing trends, and ...

Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...

Exponential nucleic acid replication can occur isothermally in a prebiotically plausible setting that accumulates and simultaneously separates the strands of nucleic acids through evaporation-driven ...

The variety of potentially useful dyes or haptenes available for fluorescent nucleic acid hybridization assays is far greater than what can be obtained from commercial sources 1,2. Since this ...

Inside our cells, ribosomes—the tireless "protein factories" of life—have just shown off a new skill they haven't used in ...

Nucleic acids is a growing research area within the School of Chemistry. Topics of interest include modified nucleic acids, nucleic acid diagnostics, single molecule imaging and microscopy, ...

The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are ...

Nucleic acids, as one kind of significant biomarker, have attracted tremendous attention and exhibited immense values in fundamental studies and clinical applications. In this work, we developed a ...