DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

In addition to the standard Watson-Crick base pairs, there are also non-canonical base pairs that can form in certain situations. These include wobble base pairs, such as G-U and I-A (inosine-adenine) ...

Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and answer questions ...

Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose.The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...

Structural comparison of DNA and the artificial TNA, a Xeno nucleic acid with the natural base pairs AT and GC and an additional base pair (XY). view more . Credit: Stephanie Kath-Schorr.

Metal-mediated base pairing in nucleic acids represents a transformative approach wherein traditional Watson–Crick hydrogen bonds are replaced or supplemented by coordinate bonds with metal ions.

We developed a nucleic acid that is able to recognize via metal-mediated base pair formation one oligonucleotide from a mixture of natural oligonucleotides that differ by a single nucleoside only.

Peptide nucleic acid, a synthetic hybrid of protein and DNA, ... or U.) Pairs of these bases joined by hydrogen bonds form the “rungs” of the familiar DNA “ladder.” ...

WEST LAFAYETTE, Ind. — A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid ...