Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for ...
Tarun Kapoor is tackling a deceptively tricky biochemical challenge: how to speed up the internal machinery of living cells.
Scientists have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known ...
Cardiovascular illnesses, such as high blood pressure and heart problems, are often treated with angiotensin-converting enzyme (ACE) inhibitors. The ACE inhibitors lower blood pressure by relaxing ...
In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, ...
Blood pressure management is important for reducing your risk of other conditions, like heart attack or stroke. Guidelines for treating high blood pressure recommend angiotensin-converting enzyme ...
The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such transporter is ...
SCOUT-HCM demonstrated the superiority of Camzyos on the primary endpoint and multiple secondary endpointsThe overall safety results in this study were consistent with the established safety profile ...