Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 12 (Mar. 21, 2006), pp. 4392-4397 (6 pages) A self-catalyzed, site-specific guanine-depurination activity ...
Depurination of DNA and RNA sequences is an alteration of the sugar-phosphate backbone in which hydrolysis of a purine base (adenine or guanine) occurs. Synthetic oligonucleotides suffer from such ...
(Nanowerk Spotlight) DNA is constantly being damaged in our cells by radiation and other random sources. There is a long list of structural and chemical variations to DNA that have impacts on human ...
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