Two harmful gene variants can restore function when combined, study reveals

Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...
eLife

Chromosomes: Finding a role for non-coding DNA in trypanosomes

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

International collaboration produces detailed models of the 3D genome over time in cells

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Searching for the centromere: Diversity in pathways key for cell division

Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material ...
Mediafeed on MSN

Do biological age tests really work?

Biological age tests measure how fast your body is aging compared to your actual age. These tests rely on biomarkers tied to ...
gmwatch.org

Gene editing disrupts multiple gene functions through large-scale epigenetic changes in a way that persists through successive cell generations

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted changes in gene function. Report: Claire Robinson and Prof Michael Antoniou ...
Medscape

Gene Therapy Shows Signal for Improving Retinal Function

A gene therapy that targets a form of retinitis pigmentosa showed a signal to improve retinal function for up to 3 years after treatment, according to a small clinical trial. The phase 2 SKYLINE trial ...
News Medical

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to ...
Scientific Research Publishing

Current Research Status of ATP6V Gene Family in Human Cancers ()

1 Department of Gastrointestinal Surgery, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. 2 School of Clinical Medicine, Youjiang Medical University for ...
GEN

Mantle Cell Lymphoma Translocations Rewire Chromosome-Wide Gene Expression

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...
eLife

Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches

This study is valuable as it provides information about the genes regulated by sex hormone treatment in song nuclei and other brain regions and suggests candidate genes that might induce sexual ...
New York Post

Could Down syndrome be eliminated? Scientists say cutting-edge gene editing tool could cut out extra chromosome

Cutting-edge gene editing technology could eradicate Down syndrome, according to Japanese scientists. Down syndrome, which causes a range of developmental differences and affects 1 in 700 newborns in ...