Traditionally, clinical genetics services offered ‘reactive’ testing of specific cancer susceptibility genes (CSGs) to those with the corresponding classical presentation. Increasingly, cancer ...

One year ago, the PHG Foundation report, Host genomics: lessons for infectious diseases, highlighted the promise of host genomics research for infectious disease. Policy priorities may have changed ...

The UK is a recognised powerhouse for genomic science and medicine. Genomics England’s 100,000 Genomes Project is the largest sequencing project of its kind in the world and, building on these ...

We are getting closer to a world where the debilitating pain and complications of sickle cell disease are a thing of the past. For the 17,500 people in the UK living with this genetic condition, this ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Inter-CeBIL is the International Collaborative Biomedical and Innovation Law program involving the law faculties at Copenhagen, Cambridge, Harvard and select other partners. PHG Foundation is ...

Regenerative medicine (RM) featured as one of the PHG Foundation’s key transformational technology areas in our recent report ‘The personalised medicine technology landscape’. We described that ...

The rapid development, approval and roll out of multiple vaccines against SARS-CoV-2, the virus that causes COVID-19, is an impressive achievement for science and healthcare. The virus genome was ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

A recent consultation by the UK Medicines and Healthcare products Regulatory Agency (MHRA) indicates a welcome new direction for public and patient involvement (PPI). The MHRA proposed new five-year ...

These plans have been a long time in the making. The intention to produce a strategy ‘to ensure the UK is able to offer a predictive, preventative and personalised health and care service for people ...