Gut10d
Histology of subepithelial lesions (SELs) in the gastrointestinal tract-resected endoscopic: a database study of 4901 patients
Subepithelial lesions (SLEs) are often detected incidentally during endoscopic examination. They represent a heterogeneous ...
gut.bmj17d
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and ...
gut.bmj2d
IDDF2024-ABS-0288 Engineered probiotic with high tryptophan synthesis capability protects against inflammatory bowel disease
1 Center for Gut Microbiome Research, Med-X Institute, The First Affiliated Hospital of Xi’an Jiao Tong University, China 2 Institute of Digestive Disease and Department of Medicine and Therapeutics, ...
gut.bmj12d
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2
Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.
gut.bmj9d
Efficient plasma metabolic fingerprinting as a novel tool for diagnosis and prognosis of gastric cancer: a large-scale, multicentre study
2 Key Laboratory of Prevention, Diagnosis and Therapy of Upper Gastrointestinal Cancer of Zhejiang Province, Hangzhou, China Objective Metabolic biomarkers are expected to decode the phenotype of ...
gut.bmj12d
Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases
Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp metabolism ...
gut.bmj12d
Angiogenin maintains gut microbe homeostasis by balancing α-Proteobacteria and Lachnospiraceae
Objective Antimicrobial peptides (AMPs) play essential roles in maintaining gut health and are associated with IBD. This study is to elucidate the effect of angiogenin (ANG), an intestine-secreted AMP ...
gut.bmj12d
Targeting the oncogenic m6A demethylase FTO suppresses tumourigenesis and potentiates immune response in hepatocellular carcinoma
Objective Fat mass and obesity-associated protein (FTO), an eraser of N 6-methyadenosine (m6A), plays oncogenic roles in various cancers. However, its role in hepatocellular carcinoma (HCC) is unclear ...
gut.bmj12d
Inflammatory bowel disease and new-onset psychiatric disorders in pregnancy and post partum: a population-based cohort study
Objective Patients with inflammatory bowel disease (IBD) have an elevated risk of mental illness. We determined the incidence and correlates of new-onset mental illness associated with IBD during ...
gut.bmj14d
Guidelines on the management of abnormal liver blood tests
These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) ...
gut.bmj12d
The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease
Background Several randomised clinical trials (RCTs) performing faecal microbiota transplantation (FMT) for the management of inflammatory bowel disease (IBD), particularly for ulcerative colitis, ...
gut.bmj11d
Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide
Correspondence to Dr Chia-Chen Lu, Department of Respiratory Therapy, Fu Jen Catholic University, New Taipei City, Taiwan; chiachen.lulu{at}gmail.com Objective Chronic obstructive pulmonary disease ...