Large-conductance calcium-activated potassium (BK) channels are critical determinants of smooth muscle function by mediating rapid feedback between intracellular calcium levels and membrane potential.

To recap, the transverse tubules are indispensable for efficient muscle function. Their key functions are: Rapidly transmit action potentials from the sarcolemma to the interior of the muscle fiber.

To understand what causes muscle fatigue, it’s worth looking at what exactly muscle fatigue is. If you exercise regularly, you may be familiar with the sensation of a dull ache in your muscles or ...