Figure 1: Synthetic strategies to access secondary and tertiary alcohols by carbonyl addition reactions. Despite considerable advances, and the abundance of organometallic reagents developed for ...

Carbonyl‐olefin metathesis reactions have emerged as an invaluable strategy for the direct formation of carbon–carbon bonds, enabling the efficient construction of complex molecular architectures.

Scientists at Scripps Research have used rapid alternating current (AC) to selectively reduce carbonyl groups (J. Am. Chem. Soc. 2021, DOI: 10.1021/jacs.1c06572). The technique avoids side reactions ...

Emory University researchers led by Kyle Biegasiewicz have repurposed enzymes to produce diazo compounds from hydrazones ...

Family of compounds known as 1,2,3,5-tetrazines could have wide application in making new pharmaceuticals, chemical and biological probes, and other products. Chemists at Scripps Research have devised ...

Penn State researchers have uncovered a surprising twist in a foundational chemical reaction known as oxidative addition. Typically believed to involve transition metals donating electrons to organic ...

This module covers aldehydes and ketones as the substrates and products of redox reactions. Structure is explained with both Lewis structures and molecular orbitals to discuss mechanisms in the ...

Halogen bonds were first proposed as an activating interaction in 2008, but this alternative type of organocatalysis was ...