Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

Scientists have found that twisting structures in DNA long mistaken for knots are actually something else entirely. Inside cells, DNA gets twisted, copied, and pulled apart. The twists can influence ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...