Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...
Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric ...
BETHESDA, Md., Oct. 30, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of ...
In a recent study posted to the bioRxiv* pre-print server, researchers investigated allosteric binders of angiotensin-converting enzyme 2 (ACE2) that significantly inhibit severe acute respiratory ...
This is a preview. Log in through your library . Abstract Ubiquitin-conjugating enzymes (E2s) collaborate with the ubiquitin-activating enzyme (E1) and ubiquitin ligases (E3s) to attach ubiquitin to ...
The findings confirm that allosteric inhibition of integrase is clinically viable, validating a new antiviral drug class.
Durability of immune checkpoint inhibitor (ICI) response following treatment discontinuation in advanced merkel cell carcinoma (MCC). The 15-gene expression profile test is independent from PRAME and ...
Chemistry professors used the Google algorithm PageRank to identify key amino acids in the regulation of a bacterial enzyme essential for most microorganisms. Yale scientists have taken a novel ...
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