Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...

DUBLIN--(BUSINESS WIRE)--Research and Markets has announced the addition of the "Nociceptin Receptor (Kappa Type 3 Opioid Receptor or KOR3 or Orphanin FQ Receptor or OPRL1) - Pipeline Review, H2 2016" ...

The new research uncovers the molecular matches for 20 olfactory receptors, paving the way for a new generation of scent ...

The research, published June 4 in Nature Structural & Molecular Biology, identifies critical connections between activity of the epilepsy drug perampanel and the resulting movements of the AMPA ...

When you're under stress, your brain may release its own cannabinoid molecules to calm you, activating the same brain receptors as THC derived from cannabis plants. But the brain activity regulated by ...

(Reuters) -Tiny viruses that only infect and kill bacteria can help treat deadly antibiotic-resistant bloodstream infections with Staphylococcus aureus, results from a mid-stage trial suggest.

In patients with severe osteoarthritis, cartilage can wear so thin that joints essentially transform into bone on bone — without a cushion between. A new therapy that uses synthetic nanofibers to ...

Finding may advance creation of new drugs that target AMPA receptors to treat brain cancer, pain and Alzheimer’s disease By super cooling a molecule on the surface of brain cells down to about minus ...