The synthesis of pyrimidine derivatives has long attracted attention due to their prominent role in pharmaceutical development and material science. In recent years, a sustainable approach utilising ...
Human cytomegalovirus (HCMV) induces numerous changes to the host metabolic network that are critical for high-titer viral replication. We find that HCMV infection substantially induces de novo ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolves rapidly under the pressure of host immunity, as evidenced by waves of emerging variants despite effective vaccinations, ...
Megaloblastic maturation is the morphologic result of any biochemical defect that causes a slowing of DNA synthesis. The hallmark of this megaloblastosis is nuclear-cytoplasmic dissociation; the ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, announced the expansion of the ...
Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new study shows. While chemotherapies successfully treat cancers and extend ...
Osaka, Japan – Malignant melanoma is a type of skin cancer that originates from melanocytes or nevi, causing about 80% of skin cancer-related deaths. While some cases have shown significant response ...
Purines are heterocyclic bases. Simply put, these are closed ring structures comprised of at least two different kinds of atoms. Purines are one of three components of nucleotides; phosphate esters of ...
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