The FDA has approved Kygevvi (doxecitine and doxribtimine) for the treatment of TK2d in adults and pediatric patients with an age of symptom onset on or before 12 years.

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

That research led to the FDA granting compassionate use of the doxecitine and doxribtimine treatment in Arturito Estopinan, ...

T he FDA approved doxecitine and doxribtimine powder (Kygevvi) for thymidine kinase 2 deficiency (TK2d), an ultra-rare ...

First-in-human trial of the oral ataxia telangiectasia and Rad3-related (ATR) inhibitor BAY 1895344 in patients (pts) with advanced solid tumors. This is an ASCO Meeting Abstract from the 2019 ASCO ...

Thymine, which is often abbreviated as T or Thy, can also be referred to as 5-methyluracil. Thymine is one of the pyrimidine bases found in the nucleic acid of deoxyribonucleic acid (DNA), along with ...

The stability of DNA is extremely important for the proper functioning of all cellular processes. Exposure to UV radiation alters the structure of DNA, affecting the physiological processes of all ...