Adenylosuccinate lyase (ADSL) deficiency is an inherited metabolic disorder that impairs purine metabolism. ADSL is a key enzyme in both the de novo synthesis and the purine nucleotide cycle, ...

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function. A recent study ...

Gut microbiota capable of metabolizing uric acid and purines may play a key role in reducing gout diagnoses, and although the findings from new retrospective and prospective studies suggest key roles ...

Efforts to combat hyperuricemia may find help from gut microbes, according to Dylan Dodd, MD, PhD, who spoke at the annual research symposium of the Gout, Hyperuricemia, and Crystal-Associated Disease ...

XORTX Therapeutics Inc. (" XORTX " or the “ Company ”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat ...