Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.
Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...
A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are ...
The new findings strengthen the "RNA world" hypothesis that describes how the first life on Earth could have used RNA instead ...
CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...
Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to ...
Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...
Researchers at Utah State University revealed new details about CRISPR immune system defenses, such as Cas12a3 systems, that ...
A breakthrough experiment, published in the Proceedings of the National Academy of Sciences, offers compelling support for ...