As the “Method of the Year 2024”, spatial proteomics (SP) enables in situ characterization of protein localization, abundance ...

Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Published in Current Molecular Pharmacology, a comprehensive review led by Yong Xu and colleagues from Shanghai Pulmonary Hospital explores the emerging role of lactylation, a post-translational ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Researchers have developed a method for studying an important, yet often overlooked, posttranslational modification.

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular ...

Integrating proteomics with systems biology reveals complex cellular networks, improving disease mechanisms understanding and precision medicine applications.