The use of in vivo electroporation (EP) as a therapeutic gene delivery approach has been successfully used in a variety of applications including cancer therapy and the regulation of protein levels to ...

Hopewell-based team delivers on ProBio's promise of speed, quality, and reliability—offering a transparent, fixed-cost model and ≥85% supercoiled plasmid DNA in record time for clinical programs. The ...

As cell and gene therapies, mRNA vaccines and other cutting-edge meds come into their own, developers have put a strain on the industry's supply chain. That’s where biopharma building block outfits ...

Success in gene and cell therapy is driving demand for plasmid DNA which is a key reagent to produce viral vectors, both for commercial products as well as the breadth of different vectors for the ...

In the development of DNA vaccines and cell and gene therapies, manufacturing plasmid DNA creates a crucial bottleneck. Such a slowdown could intensify with the market for manufacturing DNA plasmids ...

Plasmid DNA isolation from bacteria is a vital molecular biology method used to create template DNA for preferred downstream reactions. Plasmid isolation approaches are basic; however, high-throughput ...

Bacterial plasmids are circular or linear double-stranded DNA molecules defined by their capability of autonomous replication in the hosts. They are critical sources for microbial evolution and genome ...

A new partnership strengthens plasmid sequencing with high-accuracy long-read technology, improving data transparency, mutation detection, and scalability while supporting reliable, cost-effective ...

Scientists have reported large DNA structures in some archaea that defy easy categorization. When the microbiologist Jillian Banfield and her colleagues started combing through samples of mud from ...