This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...

Phosphoinositide signaling pathways have been implicated in the metabolic alterations associated with various human diseases, including breast cancer. The phosphatidylinositol-5-phosphate 4-kinase ...

Drosophila phototransduction has served as a model system for elucidating the molecular basis of sensory signal processing. In the fruitfly’s photoreceptors, light is captured by rhodopsin and ...