From The Bedalov Lab, Human Biology and Translational Science and Therapeutics Divisions Thus, the team began this current study with a scavenger hunt for a nucleosome-modifying enzyme which could ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Initiation of DNA synthesis: a general model from studies with prokaryotes -- Escherichia coli oriC -- Lambda phage origin: a familiar refrain -- Regulatory transcription factors and the initiation of ...

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off ...