Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...
In the case of nucleic acid tests, polymerase chain reaction (PCR) has been the gold standard for single-molecule diagnosis. Single-molecule detection of pathogens, such as severe acute respiratory ...
Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...
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