Chemists from the National University of Singapore (NUS) have developed a way to make diverse chiral deoxyribonucleic acid (DNA) catalysts by merging DNA repair with biorthogonal chemistry, paving the ...

A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

Shape shifts happen all around you. Cells stretch, tissues curl, and living structures shift their form as naturally as breathing. Scientists have tried to copy those abilities for years, hoping to ...

There are many health problems that can be traced back to errors in the genetic code. There are also many potential benefits to genetic engineering outside of healthcare. Nature has already found ways ...

The nucleus has historically been considered to be metabolically inert, importing all its needs through supply chains in the cytoplasm. Now, a new study by researchers at the Centre for Genomic ...

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research. In crisis, the nucleus calls ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis ...

Researchers have found new ways to string together artificial DNA bases. The techniques could aid the creation of altered genetic material for applications in medicine and technology. Floyd Romesberg ...

DNA damage is common to our cells, but when we’re young our bodies can fix it pretty easily. Unfortunately we lose that ability over time, leading to many of the symptoms of aging that we know all too ...

Homologous recombination is an ancient process that functions to conserve genetic integrity and create genetic diversity. It relies on the formation of Holliday junctions — four-stranded DNA ...

Chondrocytes play a crucial role in skeletal development. Many bones, such as those in the arms and legs, are formed through ...

Artios Pharma, which looking for newer targets that, like PARP inhibitors, affect the way tumors fix themselves, said its ...