Peptide nucleic acids (PNAs) represent a revolutionary class of synthetic nucleic acid analogues, in which the traditional sugar–phosphate backbone is replaced by a neutral N-(2-aminoethyl) glycine ...

C-H activation-based method should speed drug molecule design and diversification. Scripps Research chemists have accomplished a long elusive feat in synthetic chemistry: the invention of a broadly ...

Any project, supported or not by a committee, that is currently being worked on or is considered active, and will have an end date. Most biological molecules are chiral entities where their mirror ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Molecular dynamics (MD) simulations have emerged as a pivotal tool in elucidating the intricate behaviours of nucleic acids at the atomic scale. These computational methods offer a dynamic portrayal ...