Many antibiotics stop bacterial growth by inhibiting different steps of protein synthesis. However, no specific inhibitors of translation termination are known. Proline-rich antimicrobial peptides, a ...

Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have ...

Antimicrobial resistance is a major public health issue that contributes to the emergence of drug-resistant microorganisms, thereby increasing the risk of nosocomial infections. Short peptide ...

Over the last few decades, antimicrobial resistance has become a major public health concern globally. This has led to a search for alternative methods of treating microbial infections. One such ...

Deficiency in vitamin D is associated with numerous health conditions ranging from bone health to cancer, but with the discovery of antimicrobial peptide gene regulation by the vitamin D pathway a ...

Researchers have now developed a streamlined approach to developing artificial antimicrobial peptides. Their strategy, which relies on a computer algorithm that mimics the natural process of evolution ...

The story of antimicrobial peptides (AMPs), particularly in tackling antibiotic resistance, has been one of false dawns and unfulfilled promises. But perhaps a new generation of “smarter” compounds ...

In the summer of 1928, Alexander Fleming, an English biologist, accidentally discovered that the mold Penicillium notatum inhibits bacterial growth. Fleming’s serendipitous finding brought ...