Now, researchers at Harvard University have designed a new class of adenine base editors (ABEs) that can efficiently turn A-T into G-C, opening up the majority of pathogenic point mutations for ...

As next-generation sequencing swept across much of biology, scientists collected enormous amounts of information on the strings of bases—adenine, guanine, cytosine, and thymine—that make up DNA, but ...

The genome of every cell on Earth uses four DNA bases—adenine, thymine, cytosine, and guanine—to encode proteins. Chemists have long dreamed of expanding that set to create cells that work with both ...

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

Researchers discovered how the Lsr2 protein silences foreign DNA in tuberculosis bacteria. By forming protein condensates on ...

Scientists have developed and improved the ABE system in mouse and rat strains, which has great implications for human genetic disorders and gene therapy. Two research teams from East China Normal ...

Red arrows indicate the nuclear spin axes at the positions of the N3 nitrogen atoms on the guanine (G) bases. Due to the helical structure of DNA, there is an angular deviation in the orientation of ...