With kickoff fast approaching, we're looking at three keys for the Philadelphia defense vs. the 49ers offense.

The San Francisco 49ers will be on the road against a division rival if they're able to beat the Philadelphia Eagles in the wild card game.

The 49ers and Eagles have a rough recent history, from the Niners’ 31-7 blowout loss in the 2022 NFC Championship Game to turning the tables with a dominant 42-19 victory in the 2023 regular season. That 2023 game was the one that put Brock Purdy firmly on the map as a serious quarterback.

The 49ers are dealing with a rash of injuries, while the Eagles have been inconsistent on offense despite deep talent.

The San Francisco 49ers elevated two players from their practice squad who likely will assist on special teams for Sunday's NFL playoff matchup.

At linebacker, the 49ers are especially depleted. And while the Eagles’ offense isn’t nearly as dangerous as it was during their Super Bowl run, it still presents a tough test with reigning Super Bowl MVP Jalen Hurts leading the unit.